Novel Mask Interface for Non-invasive Ventilation

Jeremy E. Orr, MD

UC San Diego

Division of Pulmonary, Critical Care, and Sleep Medicine

Non-invasive ventilation (NIV) is increasingly used to support patients with respiratory failure

Major challenge of non-invasive ventilation: a mask interface must be used to provide therapy, and leaks around the mask are common

Leaks cause problems:

  • Compromise ventilator pressures and synchronization with the patient

  • Require staff intervention (consume valuable time + resources including PPE)

During the COVID-19 pandemic, leaks with non-invasive ventilation gained substantial attention as a source of infection spread via escaping droplets

Non-invasive ventilation was effectively banned at most institutions


Only recently with vaccination, better PPE supplies, and testing has NIV been allowed at UCSD and elsewhere.


Nonetheless, the downsides of NIV towards spread of infection remain a concern:

  • COVID-19 will not vanish

  • Vaccination efficacy wanes

  • PPE and testing supply chains get disrupted

  • Spread of infection via leaks is not unique to COVID-19


Novel mask interface: 3-D printed prototype

(US Patent Pending)

Suction channel at patient-mask interface zone

Connection to hospital wall suction (top) and standard 22 mm connector (bottom)

Advantages of suction at the interface zone:

  • Better maintenace of seal to the patient's skin

  • Evacuates leaks before they escape

Suction can maintain a seal

Suction holds even with positive pressure

We use a test box to precisely measure leak


One of several demonstrations that suction clears out the leak before it escapes into the box (i.e. "room")


Questions?

Contact j1orr@health.ucsd.edu to get more information on the project